ÌÇÐÄ´«Ã½

Skip to main content
 
Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
ÌÇÐÄ´«Ã½

Optogenetic Neuromodulation

ÌÇÐÄ´«Ã½

Optogenetic Neuromodulation EMERGING HORIZONS IN NEUROMODULATION: NEW FRONTIERS IN BRAIN AND SPINE STIMULATION Kalanithi, P. S., Henderson, J. M. 2012; 107: 185-205

Abstract

The recent development of optogenetics, a revolutionary ÌÇÐÄ´«Ã½ tool in neuroscience, portends an evolution of current clinical neuromodulation tools. A form of gene therapy, optogenetics makes possible highly precise spatial and temporal control of specific neuronal populations. This technique has already provided several new insights relevant to clinical neuroscience, from the physiological substrate of functional magnetic resonance imaging to the mechanism of deep brain stimulation in Parkinson's disease. The increased precision of optogenetic techniques also raises the possibility of eventual human use. Translational efforts have begun in primates, with success reported from multiple labs in rhesus macaques. These developments will remain of ongoing interest to neurologists and neurosurgeons.

View details for

View details for