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VISUAL EVOKED-POTENTIALS IN DEMENTIA - A META-ANALYSIS AND EMPIRICAL-STUDY OF ALZHEIMERS-DISEASE PATIENTS
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VISUAL EVOKED-POTENTIALS IN DEMENTIA - A META-ANALYSIS AND EMPIRICAL-STUDY OF ALZHEIMERS-DISEASE PATIENTS BIOLOGICAL PSYCHIATRY POLLOCK, V. E., SCHNEIDER, L. S., Chui, H. C., Henderson, V., ZEMANSKY, M., SLOANE, R. B. 1989; 25 (8): 1003-1013Abstract
A meta-analytic review of flash and pattern reversal visual evoked potential ÌÇÐÄ´«Ã½ indicates that elderly demented patients have longer P100 latencies than age-matched control subjects. In the present empirical ÌÇÐÄ´«Ã½, patients with ÌÇÐÄ´«Ã½ diagnoses of probable Alzheimer's disease were compared with sex- and age-matched control subjects using P100 latencies of visual evoked potentials (VEP) elicited by flash and pattern reversal. As compared to control subjects, Alzheimer's disease patients showed significantly longer P100 latencies of the VEP elicited by pattern reversal; the flash P100 only marginally distinguished them. These findings are discussed within the context of VEP recording practices, patient selection, sex and age matching of control subjects, and the visual system.
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