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National Effort to Re-Establish Heavy Ion Cancer Therapy in the United States.
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National Effort to Re-Establish Heavy Ion Cancer Therapy in the United States. Frontiers in oncology Pompos, A., Foote, R. L., Koong, A. C., Le, Q. T., Mohan, R., Paganetti, H., Choy, H. 2022; 12: 880712Abstract
In this review, we attempt to make a case for the establishment of a limited number of heavy ion cancer ÌÇÐÄ´«Ã½ and treatment facilities in the United States. Based on the basic physics and biology ÌÇÐÄ´«Ã½, conducted largely in Japan and Germany, and early phase clinical trials involving a relatively small number of patients, we believe that heavy ions have a considerably greater potential to enhance the therapeutic ratio for many cancer types compared to conventional X-ray and proton radiotherapy. Moreover, with ongoing technological developments and with ÌÇÐÄ´«Ã½ in physical, biological, immunological, and clinical aspects, it is quite plausible that cost effectiveness of radiotherapy with heavier ions can be substantially improved.
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