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Late Events Occurring After 5Years in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group.
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Late Events Occurring After 5Years in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group. Pediatric blood & cancer Kreimer, S., Xue, W., Qumseya, A., Lautz, T. B., Shenoy, A., Hiniker, S., Casey, D., Venkatramani, R., Arndt, C. 2024: e31421Abstract
Rhabdomyosarcoma is the most common pediatric soft tissue sarcoma, and 5-year overall survival exceeds 70%. With more long-term survivors, it is critical to understand the frequency of late events, including recurrence, second malignant neoplasm, and death, occurring 5years after diagnosis, and the variables associated with these events. We report late events in patients enrolled on Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group trials from 1997 to 2013 including D9602, D9803, D9802, ARST0331, ARST0431, ARST0531, and ARST08P1. A late event occurred in 2.9% of 5-year event-free survivors supporting guidelines to limit surveillance for these events to 5years from diagnosis.
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