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The Diagnosis and Staging of Hepatocellular Carcinoma: A Review of Current Practices.
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The Diagnosis and Staging of Hepatocellular Carcinoma: A Review of Current Practices. Clinics in liver disease Vutien, P., Kim, N. J., Nguyen, M. H. 2025; 29 (1): 33-48Abstract
Promoting the early detection and diagnosis of hepatocellular carcinoma (HCC) is a critical strategy to improve patient outcomes as this can lead to greater access to curative treatments. This review highlights the diagnostic tests for HCC, including the use of the Liver Imaging Reporting and Data System systems and histopathology. Staging is essential for informing prognosis and guiding treatment decisions; this review also covers a widely used and well-validated staging system called the Barcelona-Clinic Liver Cancer (BCLC) algorithm. The BCLC incorporates tumor status, liver function, and patient performance to stage patients with newly diagnosed HCC.
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