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A Novel Transcatheter Posterior Ventricular Anchoring Neochordoplasty Mitral Valve Repair Device.

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A Novel Transcatheter Posterior Ventricular Anchoring Neochordoplasty Mitral Valve Repair Device. Cardiovascular engineering and technology Park, M. H., Imbrie-Moore, A. M., Paulsen, M. J., Zhu, Y., MacArthur, J. W., Woo, Y. J. 2024

Abstract

Advancements in minimally invasive technologies to decrease postoperative morbidity and recovery times represent a large opportunity for mitral valve repair operations. However, current technologies are unable to replicate gold standard surgical neochord implantation.We developed a novel neochordal repair device, Minimally Invasive Ventricular Anchoring Neochordoplasty (MIVAN), which operates via transcatheter, trans-septal anchoring to the posterior ventricular wall. We evaluated MIVAN in an ex vivo heart simulator and compared it with surgical neochordal repair and MitraClip using a prolapse model.Upon MIVAN repair of the model (n?=?5), regurgitant fraction was reduced from 19.46?±?1.77% to 7.30?±?0.99% (p?=?0.01). Surgical neochordal repair reduced regurgitant fraction to 5.65?±?0.66%, but there was no significant difference between MIVAN and surgical repair (p?=?0.22). Unpaired MitraClip repair had significantly higher regurgitant fraction of 11.9?±?1.40%, compared with those of neochord (p?

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