Composite Health Assessment Risk Model (CHARM) for Older Adults (BMT CTN 1704)
Trial ID or NCT#
NCT03992352
Status
NOT RECRUITING
Purpose
Prospective observational multicenter study of allogeneic Hematopoietic Stem Cell Transplantation (HCT) in recipients 60 years and older to assess important determinants of health status to be combined into a composite health risk model to improve risk assessment of non-relapse mortality (NRM).
Official Title
Composite Health Assessment Risk Model (CHARM) for Older Adults: Applying Pre-Transplant Comorbidity, Geriatric Assessment, and BioMarkers on Non-Relapse Mortality After Allogeneic Transplant (BMT CTN 1704)
Eligibility Criteria
Ages Eligible for Study: Older than 60 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes
Inclusion Criteria:
- 1. Subject is \> 60.0 years old at time of enrollment.2. Hematological malignancy as an indication for allogeneic transplantation.3. Eligible for allogeneic transplantation based on institutional standards4. First allogeneic transplant planned. Any conditioning regimen and allogeneic donor is acceptable.5. Able to speak and read English. Spanish, and Mandarin will be acceptable when sites have ability to perform healthcare provider tests in those languages.6. Written informed consent
Exclusion Criteria:
- 1. Prior allogeneic HCT
Investigator(s)
Laura Johnston
Blood and marrow transplant specialist,
Blood and marrow transplant specialist,
Medical oncologist,
Hematologist
Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy), Emerita
Contact us to find out if this trial is right for you.
Contact
Melanie Gaudinez
650-725-4983
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